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Episode 888

Glucose-6-phosphate translocase
Wed, 2019-Oct-09 00:04 UTC
Length - 1:54

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Welcome to random Wiki of the Day where we read the summary of a random Wikipedia page every day.

The random article for Wednesday, 9 October 2019 is Glucose-6-phosphate translocase.

Glucose-6-Phosphate Translocase is an enzyme that in humans is encoded by the SLC37A4 gene. It consists of three subunits, each of which are vital components of the multi-enzyme Glucose-6-Phosphatase Complex (G6Pase). This important enzyme complex is located within the membrane of the endoplasmic reticulum, and catalyzes the terminal reactions in both glycogenolysis and gluconeogenesis. The G6Pase complex is most abundant in liver tissue, but also present in kidney cells, small intestine, pancreatic islets and at a lower concentration in the gallbladder. The G6Pase complex is highly involved in the regulation of homeostasis and blood glucose levels. Within this framework of glucose regulation, the translocase components are responsible for transporting the substrates and products across the endoplasmic reticulum membrane, resulting in the release of free glucose into the bloodstream.

This recording reflects the Wikipedia text as of 00:04 UTC on Wednesday, 9 October 2019.

For the full current version of the article, see Glucose-6-phosphate translocase on Wikipedia.

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