Currently being updated.
Automatic reload in seconds.


 
Subscribe: RSS Podcast iTunes
wikiofthedaymasto.ai
  Buy WotD Stuff!!
Episode 1537             Episode 1539
Episode 1538

Dementia with Lewy bodies
Wed, 2021-Jul-21 01:05 UTC
Length - 3:53

Direct Link

Welcome to featured Wiki of the Day where we read the summary of the featured Wikipedia article every day.

The featured article for Wednesday, 21 July 2021 is Dementia with Lewy bodies.

Dementia with Lewy bodies (DLB) is a type of dementia characterized by changes in sleep, behavior, cognition, movement, and autonomic bodily functions. Memory loss is not always an early symptom. The disease worsens over time and is usually diagnosed when cognitive decline interferes with normal daily functioning. Together with Parkinson's disease dementia, DLB is one of the two Lewy body dementias. It is a common form of dementia, but the prevalence is not known accurately and many diagnoses are missed. The disease was first described by Kenji Kosaka in 1976.

REM sleep behavior disorder (RBD)—in which people lose the muscle paralysis that normally occurs during REM sleep and act out their dreams—is a core feature. RBD may appear years or decades before other symptoms. Other core features are visual hallucinations, marked fluctuations in attention or alertness, and parkinsonism (slowness of movement, trouble walking, or rigidity). A presumptive diagnosis can be made if several disease features are present, such as symptoms or certain results of blood tests, neuropsychological tests, imaging, and sleep studies. Definitive diagnosis usually requires an autopsy.

Most people with DLB do not have affected family members, although occasionally DLB runs in a family. The exact cause is unknown, but involves widespread deposits of abnormal clumps of protein that form in neurons of the diseased brain. Known as Lewy bodies (discovered in 1912 by Frederic Lewy) and Lewy neurites, these clumps affect both the central nervous system and the autonomic nervous system. Heart function and every level of gastrointestinal function—from chewing to defecation—can be affected, constipation being one of the most common symptoms. Low blood pressure upon standing can also occur. DLB commonly causes psychiatric symptoms, such as altered behavior, depression, or apathy.

DLB typically begins after the age of fifty and people with the disease have a life expectancy of about eight years after diagnosis. There is no cure or medication to stop the disease from progressing, and people in the latter stages of DLB may be unable to care for themselves. Treatments aim to relieve some of the symptoms and reduce the burden on caregivers. Medicines such as donepezil and rivastigmine can temporarily improve cognition and overall functioning, and melatonin can be used for sleep-related symptoms. Antipsychotics are usually avoided, even for hallucinations, because severe reactions occur in almost half of people with DLB, and their use can result in death. Management of the many different symptoms is challenging, as it involves multiple specialties and education of caregivers.

This recording reflects the Wikipedia text as of 01:05 UTC on Wednesday, 21 July 2021.

For the full current version of the article, see Dementia with Lewy bodies on Wikipedia.

This podcast is produced by Abulsme Productions based on Wikipedia content and is released under a Creative Commons Attribution-ShareAlike License.

Visit wikioftheday.com for our archives, sister podcasts, and swag. Please subscribe to never miss an episode. You can also follow @WotDpod on Twitter.

Abulsme Productions produces the current events podcast Curmudgeon's Corner as well. Check it out in your podcast player of choice.

This has been Raveena Standard. Thank you for listening to featured Wiki of the Day.

Archive
2017:MayJunJulAugSepOctNovDec
2018:JanFebMarAprMayJunJulAugSepOctNovDec
2019:JanFebMarAprMayJunJulAugSepOctNovDec
2020:JanFebMarAprMayJunJulAugSepOctNovDec
2021:JanFebMarAprMayJunJulAugSepOctNovDec
2022:JanFebMarAprMayJunJulAugSepOctNovDec
2023:JanFebMarAprMayJunJulAugSepOctNovDec
2024:JanFebMar

Most Recent Episodes


Feedback welcome at feedback@wikioftheday.com.

These podcasts are produced by Abulsme Productions based on Wikipedia content.

They are released under a Creative Commons Attribution-ShareAlike 3.0 Unported License.

Creative Commons License

Abulsme Productions also produces Curmudgeon's Corner, a current events podcast.

If you like that sort of thing, check it out too!


Page cached at 2024-03-26 02:37:19 UTC
Original calculation time was 3.5748 seconds

Page displayed at 2024-03-28 08:23:01 UTC
Page generated in 0.0032 seconds